Consider Health Concerns
If you're managing ongoing health issues, you've probably already talked with your doctor about embarking on a long trip by RV. Even if the trip is approved by your doctor, it should still require some extra consideration in route planning.
Do you need to be within range of emergency services? Will you need to refill prescriptions along the way? If so, you may not want to take a meandering path through America's most remote desert highways. And how's the cell phone coverage along your route? Will you be able to call for help in an emergency?
Also, check the fine print in the information that comes with your prescriptions. Some medications need to be kept in controlled climates. If they get too hot or cold, they may lose their effectiveness, so make sure the RV is equipped to keep them safe.