What's the room configuration?
At home, parents and kids usually have separate bedrooms and bathrooms, and a whole house in which to work and play. In a hotel, however, all this activity is confined to a much smaller space. In a standard hotel room, with just two beds, this can be a hassle; luckily, many hotels offer a discounted price for adjoining rooms.
And some parents reserve a suite. For example, Embassy's two-room suites have a private bedroom for the adults and a separate living and dining area with a pullout couch for the kids. If you're planning to stay in one place for several days, you might consider reserving a suite at Residence Inn, which touts its accommodations as 50 percent larger than standard hotel rooms. Here you can stay in suites with up to two bedrooms and bathrooms, a living room and a full kitchen. With this kind of space, you'll be able to enjoy family togetherness without sacrificing privacy.