You've got a general route planned, but that's not enough. You also need specific, turn-by-turn directions to every hotel, restaurant and attraction along the way. There's nothing worse than getting lost and losing precious minutes or even hours from your vacation.
If you're lucky enough to have an in-car navigation system or portable GPS, program your destinations before you go so you don't have to type in the addresses while you're trying to drive. Some navigation systems will point out restaurants, hotels and attractions along the way -- an added bonus if you didn't plan ahead and you're not sure where you're going to be staying or eating.
Anyone who doesn't have an in-car navigation system can print out maps and driving directions from Web sites like MapQuest and Google Maps. And if you don't have a computer, get directions the old-fashioned way, by calling hotels and restaurants ahead of time and asking.